Last edited by Faelrajas
Saturday, July 25, 2020 | History

4 edition of Drug design. found in the catalog.

Drug design.

Drug design.

  • 305 Want to read
  • 38 Currently reading

Published by Academic Press in New York .
Written in English

    Subjects:
  • Pharmacology.,
  • Pharmaceutical chemistry.

  • Edition Notes

    Includes bibliographies and indexes.

    StatementEdited by E. J. Ariëns.
    SeriesMedicinal chemistry ;, v. 11
    ContributionsAriëns, E. J. ed.
    Classifications
    LC ClassificationsRM300 .D74
    The Physical Object
    Paginationv. <1-10 >
    Number of Pages10
    ID Numbers
    Open LibraryOL5315599M
    ISBN 100120603012
    LC Control Number72127678

      The book follows drug design from the initial lead identification through Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine/5(3). Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target.

    Drug Design, Discovery and Therapy: Clinical Trials and Regulatory Affairs. Computer-aided drug design (CADD) has been credited to the modern patterns in compound characterization in drug discovery following its inception in

    This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery. India. In this book we have tried to provide a coherent and rational account of the principles underlying every aspect of drug design. Special chapters are devoted on Enzyme Inhibitors and Anti-Aids Agents to explain the strategy of the discovery and development of drugs. Since theAuthor: Dr. V. M. KULKARNI, Dr. K. G. BOTHARA.


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Drug design Download PDF EPUB FB2

Classroom tested and student approved, Textbook of Drug Design and Discovery, Fourth Edition describes the manner in which medicinal chemists utilize the various Drug design. book upon which they draw and the specific strategies they employ to advance promising molecules into clinical use for 3/5(1).

Pharmacologists, chemists, and people involved in drug design will find the book invaluable. Show less Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis.

Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and information is presented in an up-to-date review form with an underlying and 5/5(2).

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Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable. Show less Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the design of artificial blood substitutes and auxin-type herbicides; the use of insect pheromones as a basis for the development of more effective selective pest control agents; and the development and application of new steric substituent parameters in drug design.

The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also.

drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.

Drug discovery and development is such a complex process to encompass in one reference book, but there are three best-sellers standing out as the most highly rated and comprehensive manuals on the topic today.

“Active Pharmaceutical Ingredients: D. Journal of Drug Design and Research is an interdisciplinary, open access, peer reviewed journal that brings about latest research in all related fields of Drug Design and Research focusing upon the successes in drug designing methodologies and new drugs that have been developed and the insights and advances from the combined use of chemical and biological research.

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design.

The Principles of Drug Design course aims to provide students with an understanding of the process of drug discovery and development from the identification of novel drug targets to the introduction of new drugs into clinical practice.

It covers the basic principles of how new drugs are discovered with. Drug Design 4th Edition by Dr. Kulkarni (Author), Dr.

Bothara (Author) ISBN ISBN Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book.

Format: Paperback. The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug by:   Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis.

The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of Edition: 1. DRUG DESIGN: STRUCTURE- AND LIGAND-BASED APPROACHES Structure-based drug design (SBDD) and ligand-based drug design (LBDD) are active areas of research in both the academic and commercial realms.

This book provides a current snap-shot of the field of computer-aided drug design and associated experimental Size: KB. Drug Design book. Read reviews from world’s largest community for readers.4/5(1).

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Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery.

(This book is a printed edition of the Special Issue Molecular Modeling in Drug Design that was published in Molecules) Download PDF Add this book to My Library. "In conclusion, this book provides a comprehensive introduction to computational drug design for scientists (e.g.

medicinal chemists and pharmacologists, particularly at industrial level) who are not familiar with computational methods and who wish to discuss simulation outcomes with colleagues from computational departments.Book Description. Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and information is presented in an up-to-date review form .Book Description.

The Organic Chemistry of Drug Design and Drug Action Third Edition represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.